FTP would be the "normal" answer to this

However you can to file-transfers with things like PCAnywhere - depends on if you want the clients to be shelling out £75 for software to basically do FTP ...

If you're having issues hosting your own FTP server, i'd recommend getting a Linux VPS from a managed VPS supplier for ~£30/month and you upload/download to/from that, and has a control panel for clients to do the same - and it all just works

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